The second edition of An Insider’s Guide to Cases in Clinical Medicine is a comprehensive and practical resource tailored for both undergraduate and postgraduate students preparing for clinical examinations. It thoroughly covers all commonly encountered cases with structured sample case sheets and detailed discussions that delve into pathophysiology and management. Serving as a companion to Insider’s Guide to Clinical Medicine, this edition offers a systematic approach to history-taking, diagnosis, and treatment planning, supplemented with visual memory aids for better retention. Unique in its inclusion of rheumatology and a full section on geriatric assessment, it is an indispensable guide for mastering clinical case discussions.